Cerebral hemorrhagic infarction as the initial manifestation of deep venous thrombosis in a child with patent foramen ovale: A case report

Dimitrios Panagopoulos,Georgios Markogiannakis,Nikos Eleftherakis,Sofia Loukopoulou

doi:10.5348/ijcri-2017115-cr-10854

Dimitrios Panagopoulos, Georgios Markogiannakis + Show 2 more

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https://doi.org/10.5348/ijcri-2017115-cr-10854

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Abstract

Cerebral hemorrhagic infarction as the initial manifestation of deep venous thrombosis in a child with patent foramen ovale: A case report

Highlights

Arterial ischemic stroke (AIS), with an estimated incidence of 1.1–4.3 per 100,000, is an important cause of morbidity and mortality in children and the recurrence risk is high
Case Report: We present the case of an 11-year-old child who presented with a symptomatology of acute ischemic stroke of unknown etiology
We present a rare clinical case of a young girl harboring a latent deep venous thrombosis (DVT), a thrombus in the right atrium with subsequent arterial ischemic stroke (AIS) of the brain, possibly due to a patent foramen ovale (PFO)∙ This was the first clinical manifestation of an otherwise unrecognized clinical condition

Summary

Introduction

Arterial ischemic stroke (AIS), with an estimated incidence of 1.1–4.3 per 100,000, is an important cause of morbidity and mortality in children and the recurrence risk is high. The diagnostic work up included an echocardiogram, which revealed a thrombus in the right atrium, in conjunction with a patent foramen ovale. An ultrasound study of the vessels of the lower extremities revealed deep venous thrombosis, which was considered to be the underlying causative. Conclusion: To the best of our knowledge, this is the first documented case of right atrial thrombus resulting from deep venous thrombosis in a pediatric patient with patent foramen ovale and associated ischemic stroke event. A discussion regarding the definition of cryptogenic stroke, its etiology and relationship with deep venous thrombosis and the currently proposed therapy, follows. Panagopoulos D, Loukopoulou S, Markogiannakis G, Eleftherakis N. Cerebral hemorrhagic infarction as the initial manifestation of deep venous thrombosis in a child with patent foramen ovale: A case report.

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