Abstract
Cerebral Germinoma as a cause of Abnormal Pubertal Development in a 16 years Old Boy
Highlights
MethodsBrain MRI, biopsy and histological examination were performed, revealing the presence of a germ cells tumor compatible with dysgerminoma with a component of embrional carcinoma
Intracranial germ cell tumors (IGCTs) represent 3-11% of paediatric brain tumors between 0 and 19 years [1,2]
IGCTs are malignant neoplasms arising from remnants of primitive germ cells that have failed to migrate to the genital crest during embryonic life [7]
Summary
Brain MRI, biopsy and histological examination were performed, revealing the presence of a germ cells tumor compatible with dysgerminoma with a component of embrional carcinoma. After initiation of replacement therapy for panhypopituitarism, the patient received chemotherapy and radiotherapy
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