Abstract

The cerebral circulatory function and metabolism in juvenile hypertension were studied in the use of nitrous oxide technique. The remarkably increased CBF and CMRO2 and the unchanged CVR in young hypertensive patients were observed when compared with the values of the young normotensive subjects and the hypertensive patients in middle aged and old aged. The mechanism of these findings in cerebral hemodynamics and metabolism were discussed. Some correlations between elevating blood pressure and increasing CBF, CVR and CMRO2 were observed. The renal function was compared with the cerebral circulatory function in essential hypertension. A considerably increased RPF in young hypertensive patients and a definite correlation between CBF and RPF in hypertensive patients were observed.

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