Abstract
Blood flow in the basilar and internal carotid arteries and diameters of middle meningeal, carotid, and cerebral arteries were measured using 3Tesla magnetic resonance angiography, at baseline, during infusion of nitroglycerin or placebo, and during a provoked attack, at 6 hrs after infusion, in 32 migraineurs, aged 18-55 years, in a study at Leiden University Medical Centre, the Netherlands.
Highlights
Nitroglycerin caused a transient vasodilatation of all blood vessels
Blood flow in the basilar and internal carotid arteries was unchanged during nitroglycerin infusion and migraine headache
Sixteen Finnish patients with xeroderma pigmentosum (XP) were followed for up to 23 years, and their neurological symptoms and course determined in a study at Turku University Central Hospital, Finland; Erasmus University, Rotterdam, The Netherlands; University of Brighton, and University of Sussex, UK
Summary
Blood flow in the basilar and internal carotid arteries and diameters of middle meningeal, carotid, and cerebral arteries were measured using 3Tesla magnetic resonance angiography, at baseline, during infusion of nitroglycerin or placebo, and during a provoked attack, at 6 hrs after infusion, in 32 migraineurs, aged 18-55 years, in a study at Leiden University Medical Centre, the Netherlands. Migraine headache was provoked in 20/27 (74%) migraineurs who received nitroglycerin, but in none of 5 patients who received placebo. Nitroglycerin caused a transient vasodilatation of all blood vessels. Blood vessel diameters were no different during a provoked migraine attack compared to baseline, nor between headache and non-headache sides.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
