Abstract
The article presents literature review dedicated to the modern aspects of a rare hereditary disease – cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Data concerning genetic features, pathogenesis, symptoms, methods of diagnosis of the disease, clinical screening of patients for further genetic testing are reviewed. Ethnic and gender characteristics of CADASIL are presented. Challengers in diagnosis are associated with subclinical course of CADASIL up to 40 years, polymorphism of symptoms, and its similarity to other vascular diseases. Pathogenetic treatment that slows the progression of the disease currently is not available.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.