Abstract
Researchers at a pediatric multiple sclerosis clinic, the Neurological Institute, Buffalo General Hospital, New York, report six (32%) of 19 patients diagnosed with acute disseminated encephalomyelitis (2005-9) who had protracted speech and language deficits and 3 having cerebellar mutism after follow-up from 6 months to 4 years.
Highlights
Researchers at a pediatric multiple sclerosis clinic, the Neurological Institute, Buffalo General Hospital, New York, report six (32%) of 19 patients diagnosed with acute disseminated encephalomyelitis (2005-9) who had protracted speech and language deficits and 3 having cerebellar mutism after follow-up from 6 months to 4 years
Quantitative MRI should be considered in patients with acute disseminated encephalomyelitis who have persistent cognitive deficits at follow-up
Cerebellar mutism usually presents as a feature of the posterior fossa syndrome, with neurobehavioral and personality changes
Summary
Researchers at a pediatric multiple sclerosis clinic, the Neurological Institute, Buffalo General Hospital, New York, report six (32%) of 19 patients diagnosed with acute disseminated encephalomyelitis (2005-9) who had protracted speech and language deficits and 3 having cerebellar mutism after follow-up from 6 months to 4 years. One third of the 19 patients had cerebellar symptoms, all under the age of 3 years at presentation. The dentate nucleus was involved in all 6 with cerebellar symptoms, but only 3 had mutism. All 3 patients with mutism continue to exhibit expressive speech, neurocognitive, and behavioral problems.
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