Abstract

Cephaloridine in ascending doses and penicillin administered with streptomycin were compared in successive trials. The patients had chronic purulent bronchitis or bronchiectasis, resistant to all previous antibiotic treatment. In a dosage of 2 G. daily, cephaloridine was inferior to penicillin with streptomycin, in one of 4 G. it was equal and in one of 6 G. superior in effect. Transient renal changes caution the use of this last dose.

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