Central Serous Chorioretinopathy With Multiple Leakage Points in a Young Female Patient Without Detected Risk Factors

Abstract

Central Serous Chorioretinopathy (CSR) is characterized by the accumulation of subretinal fluid at the posterior pole of the fundus, causing serous detachment of the neurosensory retina and / or retinal pigment epithelium. CSR typically affects young and middle-aged men between 20 and 40 years old with type-A personality and is associated with emotional stress. A 21-year-old non-pregnant female presented with a 2-day history of acute, sudden, painless loss of vision and metamorphopsia at the right eye. She complainted also for a central scotoma. On examination of the right eye, the best-corrected visual acuity (BCVA) was 3 / 10. Dilated fundus examination revealed a neurosensory serous detachment and the diagnosis of CSR was confirmed by fluorescein angiography and optical coherence tomography (OCT). Interestingly, the fluorescein angiography revealed multiple leakage points of the dye related to retinal pigmented epithelium defects, while OCT demonstrated a significantly increased retinal thickness. The most astonishing feature of this case report is that it concerns a female patient with acute CSR without any detected risk factors that was characterized by significantly high retinal thickness in OCT in parallel with multiple leakages in fluorescein angiography. As a result, CSR should be taken into account in the differential diagnosis of sudden, painless loss of vision, although the patient may be female without risk factors. doi:10.4021/jmc580w