Abstract
Introduction: Surgeons frequently struggle with determining which patients will benefit from liver transplantation. This is especially true in the case of frail patients. Until now, there were no quantitative and objective measures of frailty among transplant patients. With this work, we introduce the concept of central sarcopenia as a proxy measure for patient frailty and as a powerful predictor of post-liver transplant mortality. Methods: We identified n=207 deceased-donor liver recipients transplanted at the University of Michigan between 01/01/2002 and 12/31/2008 who had a CT scan of the abdomen in the peri-transplant period.
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