Abstract

Abstract The central projections of the rat superior sagittal sinus (SSS) sensory innervation were studied by transganglionic tract tracing techniques. Cholera toxin subunit b (CTb) or wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) was applied on the overlying dura of the SSS and labelled terminations in the brainstem and cervical spinal cord were examined under the light microscope. Labelled cell bodies were seen bilaterally in the trigeminal ganglia and in the C2 dorsal root ganglia following both CTb and WGA-HRP applications. In the brainstem, labelled terminations were mainly found in the caudal and interpolar parts of the spinal trigeminal nucleus. In the CTb cases, terminations were also found in the dorsolateral part of the cuneate nucleus.

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