Abstract
Abstract Central nervous system tumours, which can arise from any structures within the cranial vault and spinal canal, are heterogeneous with different histological subtypes. The clinical behaviour of these tumours depends on the site of disease and histologically. While most tumours are locally invasive, some have a predilection for leptomeningeal spread. The current WHO classification of tumours is based on histology, immunohistochemistry, and cytogenetics. This chapter discusses the clinical and imaging features of common types of central nervous system tumours, the role of radiotherapy, integration of systemic treatment with radiotherapy, and practical details on radiotherapy planning. It also summarizes the evidence underpinning current clinical practice.
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