Central-line associated bloodstream infections at a tertiary care hospital

Abstract

Introduction: The Central line associated bloodstream infections (CLABSI) are the bloodstream infections where central line was in situ for more than 48 hours from the time of event and the line was in place on the date of event or before that and are confirmed by lab investigation. CLABSI are becoming common hospital acquired infections in indoor patients. Materials and Methods: This was a prospective one-year study to assess the occurrence of CLABSI at a tertiary care hospital in Gujarat. The study involved all hospitalized patients having a central line access during August 2015 to July 2016. CLABSI were identified according to the ‘Center for Disease Control and Prevention’ definitions. Microsoft excel was used for calculation of CLABSI rates and other statistical analysis. Results: There was 3.69 per 1000 central line days of CLABSI. More CLABSI was seen with underlying medical co morbid conditions. In this study, there were five infections caused by ESBL producing organisms and one carbapenemase producing K. pneumoniae. This study shows multi drug resistant pathogens as causative agent of CLABSI. A higher rate of CLABSI in this study might be due to underlying co-morbid conditions. Conclusion: CLABSI is a common entity especially in ICU setting. It is more commonly seen in patients with comorbid conditions. K. pneumoniae, S. aureus and CoNS are the common pathogens isolsted in CLABSI.