CENTRAL GIANT CELL LESION IN THE MAXILLA TREATED WITH CORTICOSTEROID INFILTRATION

Abstract

The etiopathogenesis of some non-neoplastic benign proliferative lesions remain uncertain. This is the case of giant cell lesions (CGCL), which, despite their benign and asymptomatic nature, may display aggressive behavior. Clinical and radiographic aspects may vary greatly, though histopathologically, few to many multinucleated giant cells, fibroblasts, ovoid mesenchymal cells, and loosely arranged stroma are often observed. This study aimed to present the satisfactory outcome of a CGCL in the maxilla treated exclusively with intralesional corticosteroid injections in a 30-year-old patient, who was admitted to our center with an asymptomatic swelling in the region of teeth 14 and 15 and displaying radiographic features of an odontogenic cyst. Even though surgery is the first-line treatment option, intralesional corticosteroid was an effective strategy to manage a relatively large lesion. The etiopathogenesis of some non-neoplastic benign proliferative lesions remain uncertain. This is the case of giant cell lesions (CGCL), which, despite their benign and asymptomatic nature, may display aggressive behavior. Clinical and radiographic aspects may vary greatly, though histopathologically, few to many multinucleated giant cells, fibroblasts, ovoid mesenchymal cells, and loosely arranged stroma are often observed. This study aimed to present the satisfactory outcome of a CGCL in the maxilla treated exclusively with intralesional corticosteroid injections in a 30-year-old patient, who was admitted to our center with an asymptomatic swelling in the region of teeth 14 and 15 and displaying radiographic features of an odontogenic cyst. Even though surgery is the first-line treatment option, intralesional corticosteroid was an effective strategy to manage a relatively large lesion.