Abstract
Central giant cell granuloma is a benign lesion of a jaw which etiology is unknown. Histologically, hemosiderin pigments, sometimes woven bone trabeculae and hemorrhagic foci of the fibrovascular stroma are characterized by numerous clusters of multinucleated giant cells. Surgical curettage is widely used in the treatment and resection can be done in aggressive lesions. In our case report, a 17-years-old female patient visited our department with painless swelling in mandibular anterior region. On radiological examination, a pyramidal lesion was observed between the lateral and canine teeth. The lesion was excised under local anesthesia. Postoperative symptoms were not observed during radiological and clinical follow-up.DOI:10.21276/AOHDR.1894
Highlights
Central giant cell granuloma (CGCG) was thought to be a non-neoplastic, reactive lesion when first identified by Jaffe in 1953
CGCG is more general in every age group, especially in patients under 30 years of age and appears more commonly in the mandible than in the maxilla
Some researches indicated that accelerated increase and recurrence of the lesion during pregnancy and in the postpartum period, which suggests that CGCG may be hormone-dependent
Summary
Central giant cell granuloma (CGCG) was thought to be a non-neoplastic, reactive lesion when first identified by Jaffe in 1953. Most of the lesions are seen in young female patients less than 30 years of age. Clinical symptoms as non-aggressive form: painless swelling and slow progression. [3] in aggressive forms, findings such as bone destruction, pain, cortical bone perforation, and root resorption are common. [4] In this case reported a 17-years-old female patient,had nonaggressive CGCG in mandibula anterior. A 17-years-old female patient visited our department with painless swelling in mandibular anterior region. (Fig. 1) In the radiological examination pyramidal lesion was observed in between teeth with lateral and canine tooth. (Fig. 2) Buccal and lingual cortical bones were resorb but there was no resorption in the teeth’s roots. There was no evidence of recurrence till six months of follow-up
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