Abstract
We contribute with an uncommon case of central giant cell granuloma associated with central ossifying fibroma (CGCG-COF) in the mandible of a 38-year-old female patient. Clinically, painless swelling of 10 months' duration was detected in the anterior mandible, exhibiting prominent lingual cortical expansion. Imaging exams revealed an ill-defined multilocular mixed radiolucent-radiopaque lesion in the tooth-bearing area, measuring approximately 4 cm, causing root displacement of the lower incisors, canine, and premolars and causing exuberant expansion of bone cortices. Incisional biopsy was performed, and microscopic analysis revealed multinucleated giant cells in a hemorrhagic cellular stroma, intermingled with areas of benign fibro-osseous lesion. The diagnosis was CGCG-COF. Laboratory blood tests ruled out secondary hyperparathyroidism. The treatment consisted of marginal mandibular resection and the patient has been under strict follow-up over the last 4 months. We report an unusual case of CGCG-COF exhibiting clinical-radiographic features of aggressiveness, and long-term follow-up is required.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
