Central arterial pressure estimation based on two peripheral pressure measurements using one-dimensional blood flow simulation

Abstract

Aortic pressure can be estimated using one-dimensional arterial flow simulations. This study demonstrates that two peripheral pressure measurements can be used to acquire the central pressure curve through the patient-specific optimization of a set of system parameters. Radial and carotid pressure measurements and parameter optimization were performed in the case of 62 patients. The two calculated aortic curves were in good agreement, Systolic and Mean Blood Pressures differed on average by 0.5 and −0.5 mmHg, respectively. Good agreement was achieved with the transfer function method as well. The effect of carotid clamping is demonstrated using one resulting patient-specific arterial network.