Cemented is not superior to cementless total knee arthroplasty for complications: a propensity score matched analysis.

Abstract

There is continued debate regarding the survivorship and revision rate of cementless versus cemented total knee arthroplasty (TKA) prostheses. This includes the assessment of early revision surgery due to aseptic loosenings and periprosthetic joint infections (PJIs). Studies have not always taken into account the impact of comorbidities, such as diabetes, obesity, and tobacco. Therefore, we compared revisions in a large population of patients undergoing cemented or cementless TKAs at 90days, 1year, and 2years. A review of an administrative claims database was used to identify patients undergoing primary TKA, either cementless (n = 8,890) or cemented (n = 215,460), from October 1, 2015 to October 31, 2020. Revision surgery for PJI and aseptic loosening were identified with diagnosis and associated procedural codes at 90days, 1year, and 2years and then compared between groups. A propensity matched-analysis was performed for age, sex, Charles Comorbidity Index (CCI) > 3, alcohol abuse, tobacco use, obesity, and diabetes. Chi square tests assessed statistical significance of differences in the matched cohorts using odds ratios (ORs) with 95% confidence intervals (CIs). A P < 0.05 was defined as statistically significant. Cementless TKA was associated with similar revisions rates due to PJIs at 90days (OR, 1.04, 95% CI 0.79-1.38, p = 0.83), 1year (OR, 0.93, 95% CI 0.75-1.14, p = 0.53, and 2years (OR, 0.87, 95% CI 0.73-1.05, p = 0.17) in comparison to the cemented TKA cohort. The odds ratio of revision due to aseptic loosening was similar as well at 90days (OR, 0.67, 95% CI 0.34-1.31, 0.31), 1year (OR, 1.09, 95% CI 0.73-1.61, p = 0.76), and 2years (OR, 1.00, 95% CI 0.73-1.61, p = 0.99). This study found a comparable risk of PJI and aseptic loosening in cementless and cemented TKA when controlling for several comorbidities, such as tobacco, diabetes, and alcohol. Therefore, with proper patient selection, cementless TKAs can be performed with expectation of low risks of infections and aseptic loosenings.