Abstract

1. 1. The effects of ethanol and acetaldehyde upon adenine nucleotide concentrations in rat heart and liver were determined. 2. 2. Ethanol administered either acutely (8 g kg 0.73) or chronically (20% solution in drinking water for 21 d) significantly decreased ATP concentrations, adenylate energy charge (EC) and adenylate kinase mass action ratio ( Γ AK) in liver but affected Γ AK only in heart. 3. 3. Acetaldehyde treatment elicited similar effects but of lesser magnitude.

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