Abstract
Scarring is a natural response following wound healing and includes mature and pathological scars. Pathological scars such as hypertrophic scars (HTS) and keloids are commonly seen in burns and other traumatic injuries to the deep dermis of the skin. HTS are hypervascular, red, raised, and pruritic scars, which are normally confined to the boundary of the original injury, and can remodel into mature scars but often over prolonged periods of time. The development of HTS can lead to physical disfigurement, contractures, and loss of function. Despite many treatment options, there are no modalities available for the prevention or complete reversal of scar formation. Therefore, an updated cellular and molecular understanding of the pathophysiology of HTS is important in order to develop promising novel therapies that can benefit the patients and their care-providers.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
