Abstract
Cellular and Molecular Characteristics of Established Childhood Soft-Tissue Sarcoma Cell Lines
Highlights
Soft-tissue sarcomas originate from immature embryonal mesoderm or mesenchymal tissues, and can potentially develop from any anatomical site
We discussed the establishment of 16 cell lines from 12 neuroblastoma patients and their characteristics [29]
We provided an overview of the establishment of 13 soft-tissue sarcoma cell lines, including two alveolar RMS cell lines and one MYCN-amplified and overexpressed RMS cell line
Summary
Soft-tissue sarcomas originate from immature embryonal mesoderm or mesenchymal tissues, and can potentially develop from any anatomical site. Recent advances in progressive therapy have led to a high cure rate for soft-tissue sarcomas with combinations of chemotherapy, surgery, radiation therapy, and supportive therapy. Chromosomal analysis and more recent advanced molecular biological techniques that can identify chromosomal aberrations have improved both the diagnosis and prognosis of the disease, along with insight into the underlying mechanism of tumor biology
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Cancer Research and Therapeutic Oncology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
