Abstract
Dacron hubs anchored by polyethylene sutures in the center of vascular prostheses were placed in the thoracic aortas of growing young pigs and adult dogs. This permitted cells in the blood-stream to settle, grow, and differentiate on the hub. The nature of the cells was studied by special histologic techniques and electron microscopy. Endothelial cells covered the hub. Between the endothelium and the dacron, and close to the dacron, there were giant cells of the foreign body type. Beneath the endothelium there were fibroblasts and smooth muscle cells. The covering of the hub was identical to the inner lining of the dacron vascular prosthesis to which the hub was anchored.
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