Abstract

Immunoperoxidase and autoradiographic techniques were used to examine smooth muscle myosin-containing cells in the injured zone during rat myocardial infarction healing. It was discovered that smooth muscle myosin-containing cells occurred on the 3d day of myocardial infarction and persisted during four months of experiment. The relative volume of the cells did not exceed 5% of the total tissue volume in the injured zone. The number of these cells in the subendocardial area was greater than that in the center of the infarction area throughout all the stages of experiment. Only a few smooth muscle myosin-containing cells included 3H-thymidine, which points to a weak proliferative activity of these cells.

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