Abstract
Cardiovascular injury is a major cause of morbidity and mortality and a major public health problem especially in developed countries. Various therapies for cardiovascular injury are researched actively and have been performed clinically. Recently, a cell-based therapy appears and is focused as an alternative therapy for cardiovascular injury. Scaffold-based and cell sheet-based tissue engineering contribute to the enhancement of cell transplanting efficiency, resulting in the induction of effective therapy. These cell-based regenerative therapies have promising and enormous possibilities for curing cardiovascular injury, and the clinical trials have been started. This chapter summarizes cell-based therapies including (1) cell injection therapy and (2) scaffold-based and (3) cell sheet-based tissue engineering. In addition, cell sources are also discussed.
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