Cell to Cell Signals in Mammalian Development

Abstract

I. Homeodomain Containing Genes: Structure and Role in Development.- The Murine Homeobox Protein Hox 1.1 is Differentially Expressed in Embryonal Mesoderm and Ectoderm.- Structure, Expression and Evolutionary Relationships of Murine Homeobox Genes in the Hox 2 Cluster.- Regulation of Expression of the Hox 2.3 Gene.- The Mouse Err-1 Gene Encodes a Nuclear Protein Expressed in the Nervous System of the Developing Embryo.- The Hox 1.3 Horneo Box Gene Encodes a Sequence Specific DNA Binding Phosphoprotein.- Analysis of Transcription of the Murine Homeobox Gene Hox 1.3.- The Human Cognate of the Murine Hox 1.3 Horneo Box Gene is Almost Identical to its Murine Counterpart.- Temporal and Cellular Specificity of Expression of the Murine Homeobox-containing Gene Hox 1.4.- Murine Homeo-Genes: Some Aspects of their Organisation and Structure.- II. Extracellular Matrices and Cell Adhesion Molecules.- Cell Adhesion in Morphogenesis.- Generation of Diversity in the NCAM Adhesion Protein of Rodents.- Ultrastructural Localization of the Cell Adhesion Molecule Uvomorulin using Site-directed Antibodies.- III. Growth Factors, Receptors and Oncogenes: Structure and Function.- Mutational Analysis of the EGF Receptor Proto-Oncogene.- Activation of the human epidermal growth factor receptor.- Insulin Receptor Tyrosine Kinase and Insulin Action.- The Macrophage Colony Stimulating Factor, CSF-1, and its Receptor (c-fms).- Signal Transduction by Growth Factor Receptors.- IV. Growth Factors, Receptors and Oncogenes: Role in Differentiation and Development.- Growth and Differentiation Factors of Embryonic Stem Cells.- Regulation of Growth Factors and their Receptors in Early Murine Embryogenesis.- Mesodermal Differentiation of Embryonal Carcinoma Cells in Coculture with Visceral Endoderm Cell Lines.- Platelet-derived Growth Factor and its role in Mitogenesis and Transformation.- The Role of Polypeptide Growth Factors in Phenotypic Transformation of Normal Rat Kidney Cells.- Functions of the erbA and erbB Oncogenes in Avian Erythroblastosis.- c-fos and Polyoma Middle T Oncogene Expression in Transgenic Mice and Embryonal Stem Cell Chimaeras.- Expression of Proto-oncogene int-1 is Restricted to Specific Regions of the Developing Mouse Neural Tube.