Abstract
Abstract The effects of tetracycline, phenol, chloramphenicol and ampicillin on the rates of division and mass increase in growing cultures of Escherichia coli have been examined by comparing the number, carbon content and the size of the cells from partially inhibited cultures with those of control cultures. In cultures treated with low concentrations of tetracycline, phenol or chloramphenicol the increase in cell mass is inhibited more than cell division, thus causing a decrease in the cell size. At higher concentrations of these agents and at all concentrations of ampicillin, cell division is inhibited more than increase in cell mass so causing an increase in cell size.
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