Abstract

Cell signalling is a complex process of communication among cells and organs that governing cellular activities and cooperative cellular function. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development like tissue repair, immunity as well as normal tissue homeostasis. We have attempted to show that cell signalling (or information transmission) is associated with the entropy change of the cellular system. Disordered (higher entropy) diseased cells produce error signals in cellular information processing. Error signals are responsible for diseases such as cancer, autoimmunity, and diabetes and what not. Every disorder for any internal or external reason is associated with the entropy change of the system. We have shown that entropy change and information (cell to cell communication) are related. By understanding cell signalling or the change of entropy, diseases may be treated effectively and, theoretically, artificial tissues may be regenerated.

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