Cell Resistance and Antimicrobial Resistance with Waning Vaccination

Abstract

Viruses are obligatory minute intra-cellular infectious agents with very simple composition. They are nonliving (not active) macromolecules outside the host cell while turning into living active organisms inside host cells. The genetic material (DNA or RNA) carrying the information is crucial for virus replication and enforces the cell to approve virus replication. Consequently, it is cellular resistance against the virus that determines whether a cell at any site is infected or not. In this study, we are interested in the resistance of cells which may be infected by some disturbance such as a function of [Formula: see text] or as a random variable. Antimicrobial resistance (AMR) is the wider word for resistance in various kinds of microorganisms and includes resistance to antibacterial, antiviral, anti-parasitic, and anti-fungal medicines. Here we study the AMR problem and also, the waning vaccination in the Percolation area. Percolation is a purely geometric problem in which clusters of connected sites or bonds are clearly defined static objects. We are studying cellular automata from Domany–Kinzel on the population of AMRs as on the spreading network. Each connection is rewired on a one-dimensional chain and combined with any probability p node. Additionally, the Domany–Kinzel model will be applied for AMR and waning vaccination in two dimensions.