Abstract

IN extending our recently published work on cell growth and the development of tumours1, we have observed that in the livers of rats fed 2-acetylamino-fluorene the cell proliferation continues at a constant rate during the pre-cancerous period arid does not decrease as we had at first supposed. Such continuous increase in a cell population at a constant rate constitutes a most unusual form of growth, and it affords an important insight into the dynamics of cell proliferation in a pre-neoplastic tissue.

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