Abstract

Cell membrane-coated nanoparticles are made by wrapping natural cellular membranes onto synthetic nanoparticle cores. They leverage cell membranes to mimic some cell-like functions for biointerfacing, making it possible to enable novel biomedical applications. In this article, we review cell membrane-coated nanoparticles based on the source cell types. We focus on the biomedical applications in drug delivery, detoxification, immune modulation, and detection for each kind of cell membrane-coated nanoparticles. Overall, cell-like nanoparticles represent a new nanomedicine research area with plenty of room for development. We hope the existing studies will inspire researchers to refine existing workflows while seeking new and exciting applications.

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