Abstract
Research of nanotechnology for cancer therapy and diagnosis extends beyond drug delivery into the targeted site or surveillance the distribution of nanodrugs in vivo or distinction tumor tissue from normal tissue. To satisfy the clinic needs, nanotheranostic platform should hide the surveillance by immune system and the sequestration by filtration organs (i.e., liver and spleen). Use of biologically derived cellular components in the fabrication of nanoparticles can hide these barriers. In this review, we update the recent progress on cell membrane-coated nanoparticles for cancer theranostics. We hope this review paper can inspire further innovations in biomimetic nanomedicine.
Highlights
Cancer is known to be the most aggressive malignancy to humans, and definitely the major cause of death worldwide (Roma-Rodrigues et al, 2019)
We briefly summarized the recent progress in the development of biomimetic cell membrane camouflaged nanocomplex for cancer theranostic
This review has highlighted the current development of cell membrane coated nanoparticles for cancer theranostic
Summary
Cancer is known to be the most aggressive malignancy to humans, and definitely the major cause of death worldwide (Roma-Rodrigues et al, 2019). Cell membrane coated biomimetic nanoplatforms are often semi-biological (or semi-artificial) which take advantages of their inherited property, such as biointerfacing, self-identification and signal transduction can escape from biological barriers such as immune clearance, opsonization, and negotiation with vascular system (Evangelopoulos and Tasciotti, 2017; Chen et al, 2019; Jin et al, 2019; Madamsetty et al, 2019; Yan et al, 2019; Ma et al, 2020a) These theranostic nanoplatforms have the potential to play an important role in cancer diagnosis and treatment (Bose et al, 2018a; Li Z. et al, 2018; Meng et al, 2018; Sung et al, 2019; Ye S. et al, 2019). We demonstrated the highlight in the recent research about biomimetic cell membrane camouflaged nanocomplex on cancer theranostic
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