Abstract

Introduction 62 The Murine Major Histocompatibility Complex . 63 T Cell Subsets 64 M ethodology 65 The Response of Cytotoxic T Lymphocytes (CTLs) to Allogeneic Cells 65 The Response of CTLs to Virus-Infected Cells ... 66 Viral Requirements for Target Cell Recognition .. 67 The Response of CTLs to Viral Glycoproteins .... 68 Viral genetics 68 Viral m utants 69 Inhibition of cytolysis by antiserum 70 Stimulation of CTLs with purified viral antigens . 71 Is There a Physical Interaction Between Viral Antigens and Those of the Major Histocompatibility Com plex? 73 Conclusion 74

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