Abstract
Cytotoxicity tests were performed on cultured rheumatoid synovial membrane cells with autologous lymphocytes as effector cells. Three of 26 cultures were positive when tested at primary or first passage level, but on subsequent tests became negative. Tests based on an isotope-labelling technique and a micro-cytotoxicity assay were compared; the results appeared to correlate well. The expression of neoantigens on synovial cells was not demonstrated. Cultures initiated in medium containing hydrocortisone did not give rise to a population of synovial cells susceptible to immune lysis by autologous lymphocytes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
