Abstract
Emerging of donor specific antibodies (DSA) following transplantation is an indicator of allogenic sensitization and a predisposing factor for antibody mediated rejection. Though various methods of alloantibody detection exist, a timely and accurate test to identify allo-sensitization has not been clinically available. We report here, a study of blood CD38+/CD138+ plasma cells during the development of DSA responses in an attempt to develop a new tool for early diagnosis of allo-sensitization.
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