Abstract
Levonorgestrel (LNG) is a progestin used for emergency contraception (EC) within 72h of unprotected sexual intercourse. Selective progesterone receptor (PR) modulators (SPRMs) are PR ligands with agonist or antagonist effects on progesterone-responsive tissues. A dose of SPRM ulipristal acetate (UPA) is an effective EC alternative used up to 5-days after unprotected intercourse. In clinical studies, UPA inhibits follicle growth and ovulation. In other forms, both are effective for long-term contraception.
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