Cell coated mesh in Lichtenstein hernia repair: An open label trial

Abstract

Background: Hernia is the common problem. It is estimated that 75% all abdominal hernia occurs in inguinal region. Operation is the only treatment and standard Lichtenstein hernia repair is the one of the popular method commonly used. But there are some postoperative complications like chronic groin pain and discomfort, seroma formation and mesh migration are associated with it. Aim: To compare the effectiveness of standard Lichtenstein repair versus autologous bone marrow cell coated mess in Lichtenstein repair. Methods: This is an open label trial is conducted in department of general surgery, VIMSAR, Burla, Odisha over the period of 2 years. 128 patient falling into the inclusion criteria taken to study with randomisation. 64 in each group. Assessment of postoperative complication, recovery timing, duration of hospital staying and chronic groin discomfort is recorded. Results: Postoperative complications like cord oedema, scrotal oedema, surgical site infection, seroma, fever, discharge from wound, chronic groin pain and foreign body sensation significantly less in autologous bone marrow cell coated mesh hernia repair compared to standard Lichtenstein repair. Conclusion: The result of autologous bone marrow cell coated mesh repair is better than the result after standard Lichtenstein repair.