Cell adhesion of F + ion implantation of intraocular lens

Abstract

The cell adhesion of ion implanted polymethylmethacrylate (PMMA) intraocular lens was studied using cultured cells in vitro. F + ion implantation was performed at the energies of 40, 60, 80, 100 keV with the fluences ranging from 5 × 10 13 to 1 × 10 15 ions/cm 2 at room temperature. The cell adhesion tests gave interesting results that the number of the neutral granulocytes and the macrophages adhering on surface were reduced significantly after ion implantation. The optimal fluence was about 4 × 10 14 ions/cm 2. The hydrophobicity imparted to the lens surface was also enhanced. The results of X-ray photoelectron spectroscopy analysis indicated that ion implantation resulted in the cleavage of some pendant groups, the oxidation of the surface, and the formation of some new chemical bonds, which was probably the main reason for the cell adhesion change.