Abstract
The incidence of silent celiac disease (CD) in children with idiopathic localization epilepsies and the indications for routine CD screening were determined in a study of 72 patients (31 girls and 41 boys; mean age 12.6 years; age at onset 6.4 years) observed over a 5 year period at the Institute of Neurology and Gastroenterology, University Magna Graecia of Catanzaro, Italy.
Highlights
The incidence of silent celiac disease (CD) in children with idiopathic localization epilepsies and the indications for routine CD screening were determined in a study of 72 patients (31 girls and 41 boys; mean age 12.6 years; age at onset 6.4 years) observed over a 5 year period at the Institute of Neurology and Gastroenterology, University Magna Graecia of Catanzaro, Italy
Two palieuis (8%) in the childhood partial epilepsy with occipital paroxysms (CPEO) group had antiendomysium immunoglobulin (Ig) A antibodies, and their jejunal biopsies showed atrophy of the villi and hyperplasia of crypts, confirming the diagnosis of CD
Celiac disease screening is recommended in patients with childhood partial epilepsy with occipital paroxysms (CPEO)
Summary
A specific effect of the anticonvulsant medication on growth and bone mass is unproven, further studies are indicated. The incidence of silent celiac disease (CD) in children with idiopathic localization epilepsies and the indications for routine CD screening were determined in a study of 72 patients (31 girls and 41 boys; mean age 12.6 years; age at onset 6.4 years) observed over a 5 year period at the Institute of Neurology and Gastroenterology, University Magna Graecia of Catanzaro, Italy. The enzymelinked immunosorbent assay (ELISA) for antigliadin antibodies (AGA) and the immunofluorescent undirected test for antiendomysium antibodies (AEA) were used to confirm a diagnosis of CD.
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