Abstract

Ceftriaxone-Resistant<i>Neisseria gonorrhoeae</i>, Japan

Highlights

  • To the Editor: Spread of multidrug-resistant Neisseria gonorrhoeae is a major public health concern

  • We identified a novel ceftriaxone-resistant N. gonorrhoeae isolated from a 31-year-old female commercial sex worker; MIC of ceftriaxone for this isolate was high (2 μg/mL)

  • We compared SpeI-digested genomic DNA banding patterns of strain H041 with those of other N. gonorrhoeae strains by using pulsed-field gel electrophoresis as described [8]

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Summary

Introduction

To the Editor: Spread of multidrug-resistant Neisseria gonorrhoeae is a major public health concern. Even an extended-spectrum oral cephalosporin-resistant, cefiximeresistant N. gonorrhoeae has emerged, and cefixime has been withdrawn from use in Japan. The emergence of ceftriaxone-resistant N. gonorrhoeae threatens effective disease control. We identified a novel ceftriaxone-resistant N. gonorrhoeae isolated from a 31-year-old female commercial sex worker; MIC of ceftriaxone for this isolate was high (2 μg/mL).

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