Abstract
This case report describes neurotoxicity in an older patient on cefepime 2 g twice a day. The 81-year-old male patient developed non-convulsive status epilepticus during cefepime treatment with 1 g twice a day. There was recovery 30 days after discontinuation of cefepime.
Highlights
The existence of acute confusional states associated with the use of cephalosporins in patients with variable degrees of renal failure has been well described
A dose of 1 g every 24 hours is recommended for patients with glomerular filtration rate (GFR) lower than 10 ml\ min[8]
Renal function decreases and it is important to adjust the cefepime dose when creatinine clearance is lower than 50 ml\min[10]
Summary
Encefalopatia induzida por cefepime em paciente sem insuficiência renal Fernando Morgadinho Santos Coelho, Maurício Bernstein, Paula Kiyomi Onaga Yokota, Rosilene Motta Elias Coelho, Marcelo Wachemberg, Letícia Pereira de Brito Sampaio, Luis Otávio Caboclo
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