Abstract

Cecropins are potent basic antibacterial peptides that play a key role in insect immunity . Recently an antibacterial peptide with 33% homology to insect cecropins was isolated from extracts of the pig upper small intestine. It was postulated that production of this cecropin (named P1 for porcine) and other antibacterial peptides could contribute to regulation of the concentration of e.g. Escherichia coli in the upper part of the intestine. To further elucidate this hypothesis we have raised antibodies to cecropin P1 and localized cecropin P1-like immunoreactivity (LI) by immunohistochemistry

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