Abstract
Semiconductor nanoparticles are promising fluorescent markers. However it is very little known about interaction of quantum dots with biological molecules. In this study interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine serum albumin was investigated. Steady state and time resolved spectroscopy and atomic force microscopy methods were used. It was explored how bovine serum albumin affects stability and spectral properties of quantum dots in aqueous media. CdTe-TGA quantum dots in aqueous solution appeared to be not stable and precipitated. Interaction with bovine serum albumin significantly enhanced stability and photoluminescence quantum yield of quantum dots and prevented from aggregating.
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