Abstract
Cadherin Related Family Member 3 (CDHR3) is the receptor for Rhinovirus-C and expressed in sinonasal epithelial cells. We have previously determined that the CDHR3 (rs6967330) base change from G to A causes a two-fold increase in the odds of adults with chronic rhinosinusitis (CRS) and that RV-C infections result in increased CRS severity. However, the influence of the rs6967330 SNP on CRS disease is not known.
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