Abstract
Several years ago, the National Cancer Institute (NCI) embarked on an effort to standardize data collection methods across the cooperative trials groups it funds. These data collection methods included common toxicity criteria (CTC) and common data elements (CDEs). To date, CDEs have been developed for phase III therapeutic trials related to breast, prostate, lung, and colon cancer. Recently, the NCI funded the American College of Radiology Imaging Network (ACRIN, http://www.acrin.org), a cooperative group dedicated to imaging trials. Simultaneously, new imaging tests have shown promise in screening for lung cancer. Thus, several groups within the NCI became keenly interested in developing CDEs for imaging trials. What follows is a description of the development of CDEs for chest CT screening for lung cancer that was undertaken in the last half of 1999.
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