Abstract

Objectives: CD44, a stem cell marker, is a multifunctional transmembrane glycoprotein that binds hyaluronic acid and components of extracellular matrix (ECM), mediates cell-cell adhesion and cell-matrix interaction, and regulates cell proliferation, survival, and migration. The objective of our study was to correlate CD44 immunohistochemical expression in the four major subtypes of breast carcinoma (Luminal A, Luminal B, HER2, and triple …

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