Abstract
Meeting abstracts To investigate the relationship between tumor-associated CD40 expression, RCC patient survival and tumor stage. The expression of CD40, TUNEL and CD8 in human renal cell carcinomas was analyzed by immunohistochemistry. Computer-assisted quantitation of protein expression was used
Highlights
Experimental design The expression of CD40, TUNEL and CD8 in human renal cell carcinomas was analyzed by immunohistochemistry
CD40 expression in renal cell carcinoma correlates with tumor apoptosis, CD8 T cell frequency and patient survival
We show for the first time that tumor-associated CD40 expression correlates with prolonged survival in RCC patients
Summary
Experimental design The expression of CD40, TUNEL and CD8 in human renal cell carcinomas was analyzed by immunohistochemistry. CD40 expression in renal cell carcinoma correlates with tumor apoptosis, CD8 T cell frequency and patient survival Jonathan M Weiss1*, Gregory Alvord2, Octavio A Quinones2, Jimmy K Stauffer1, Robert H Wiltrout1
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