CD4 T CELL LYMPHOPROLIFERATIVE DISORDER ASSOCIATED WITH THE PRIMARY EAR EPSTEIN BARR VIRUS

Brady E Beltran,Esther Cotrina,Jhony A De La Cruz-Vargas

doi:10.25176/rfmh.v18.n2.1289

Abstract

Two cutaneous entities related to EBV are recognized in the 2016 World Health Organization (WHO) classification: Hydroa vacciniforme–like lymphoproliferative disorder and  Extranodal NK/T-cell lymphoma, nasal type. Rare cases of EBV primary cutaneous CD8-positive T lymphomas have been reported. These lymphoid proliferations do not fit into any of the two classical EBV-related lymphomas .We report a unique case of an  Epstein-Barr Virus-associated Primary Cutaneous –CD4-positive T-Cell Lymphoproliferative Disorder  affecting the bilateral ears  with indolent outcome and subsequent relapse on the tongue and trunk skin. Key words: EBV; CD4; lymphoma; Skin; Ear. (source: MeSH NLM)   DOI: 10.25176/RFMH.v18.n2.1289

Highlights

Two cutaneous entities related to EBV are recognized in the 2016 World Health Organization (WHO) classification: Hydroa vacciniforme–like lymphoproliferative disorder and Extranodal NK/T-cell lymphoma, nasal type
These lymphoid proliferations do not fit into any of the two classical EBV-related lymphomas .We report a unique case of an Epstein-Barr Virus-associated Primary Cutaneous –CD4-positive T-Cell Lymphoproliferative Disorder affecting the bilateral ears with indolent outcome and subsequent relapse on the tongue and trunk skin
Indolent CD8+ lymphoid proliferation on the face: part of the spectrum of primary cutaneous small-/medium-sized pleomorphic T-cell lymphoma or a distinct entity? J Cutan Pathol 2009; 37: 977

Summary

ARTÍCULO DE REVISIÓN

DESORDEN LINFOPROLIFERATIVO DE CÉLULAS T CD4 ASOCIADO AL VIRUS EPSTEIN BARR PRIMARIO DE OREJA. CD4 T CELL LYMPHOPROLIFERATIVE DISORDER ASSOCIATED WITH THE PRIMARY EAR EPSTEIN BARR VIRUS. En la clasificación de la Organización Mundial de la Salud (OMS) del 2016 se reconocen dos entidades cutáneas relacionadas con el EBV: el desoerden linfoproliferativo tipo Hydroa vaciniforme y el linfoma extraganglionar NK / T de células nasales. Se han informado casos raros de linfoma T primario CD8 cutáneo EBV positivo. Estas proliferaciones linfoides no encajan en ninguno de los dos linfomas clásicos relacionados con EBV. Presentamos un caso único de un trastorno linfoproliferativo de células T primario cutáneo-CD4-cutáneo asociado con el virus de Epstein-Barr que afecta los oídos bilaterales con curso indolente y recaída posterior en la piel de la lengua y el tronco

REPORTE DE UN CASO

CONCLUSIÓN

REFERENCIAS BIBLIOGRÁFICAS