CD19 and CD24 in beta thalassemia major and iron deficiency anemia in children

Hanan Kamel,Nagwa Diab,Alaa Rashed,Gehan Abdel Hakim

doi:10.21608/mjmr.2022.222872

Abstract

CD19 and CD24 in beta thalassemia major and iron deficiency anemia in children

Highlights

Abstracts Introduction: β-Thalassemia major is a hereditary hemolytic anemia caused by defect in β globin chain synthesis
Thirty beta thalassemia major children, thirty iron deficiency anemia children and thirty apparently healthy children as control, their age ranged from 9 months to 12 years
They were selected from out-patient clinics and those who were admitted in Pediatric department in Minia University hospital from June 2017 to March 2018

Summary

Introduction

Thalassemia major is a hereditary hemolytic anemia caused by defect in β globin chain synthesis. It is considered the most common hemoglobinopathy in Egypt and is one of the major health problems in our locality (Zahran et al, 2016). Long life blood transfusion is the main supportive treatment of this disorder. The beneficial effect of regular blood transfusion is to maintain growth and development during childhood (Elsayh et al, 2016). Iron deficiency is the most common cause of anemia worldwide, it is a state of low total body iron content. Iron deficiency anemia develops when body iron stores are depleted, level of circulating iron is reduced and there is insufficient iron available for erythropoiesis (Naqash et al, 2018)

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