Abstract
The nail unit is one of the specialized structures of the skin, and it consists of the nail plate, nail bed, nail matrix, cuticular system, nail folds and anchoring system of ligaments [ [1] Fleckman P. Anatomy and physiology of the nail. Dermatol Clin. 1985; 3: 373-381 PubMed Google Scholar ]. The research on the nail has been focused on the epithelial components in the nail unit that is known to produce most of the nail plate [ 2 De Berker D. Angus B. Proliferative compartments in the normal nail unit. Br J Dermatol. 1996; 135: 555-559 Crossref PubMed Google Scholar , 3 De Berker D. Wojnarowska F. Sviland L. Westgate G.E. Dawber R.P. Leigh I.M. Keratin expression in the normal nail unit: markers of regional differentiation. Br J Dermatol. 2000; 142: 89-96 Crossref PubMed Scopus (100) Google Scholar ]. However, little is known about the mesenchymal cells in the nail unit.
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