Cd(ClO4)2∙xH2O as a novel catalyst for the synthesis of α-aminophosphonates under solvent-free conditions

Abstract

Abstract In this paper, we report cadmium perchlorate hydrate to be an novel, expeditious catalyst for the three-component one-pot reaction of an amine, an aldehyde and a H-phosphonate diesters in open air without any solvent, leads to α-aminophosphonates in excellent yields. To the best of our knowledge this finding is the first example of a cadmium perchlorate hydrate catalyzed Kabachnik-Fields reaction.