Cd 2(tren) 2(dl-alaninato)](ClO 4) 3: an efficient water-compatible Lewis acid catalyst for chemo-, regio-, and diastereo-selective allylation of various aldehydes

Abstract

The use of [Cd 2(tren) 2(dl-alaninato)](ClO 4) 3·H 2O ( I) (tren = tris(2-aminoethyl)amine) as an efficient water-compatible Lewis acid catalyst for the allylation of aldehydes in aqueous media was described. The reaction proceeded smoothly to afford the corresponding homoallyl alcohols in up to 96% yield. Additionally, cinnamyltributylstannane was selected as the allylation reagent, the regio- and diastereoselectivity of the reaction favors the formation of the γ-product and the anti isomers, respectively.